Current Rotation Opportunities

The faculty listed are interested in taking new students.  To search for a particular name, program, or research interest, type Ctrl+f followed by the desired text.  Then press enter.

Name
Program(s)
Research Focus
Alcorn,
John F.
Immunology

Influenza and bacterial pneumonia; Severe asthma; T cells;  TH17 immunity; Host defense; Pulmonary fibrosis; Lung injury; Translational research

Ambrose, ZandreaMolecular Virology & Microbiology

Identification, characterization and eradication of HIV reservoirs; Understanding HIV drug resistance; Understanding the early infection of HIV

Anderson, Carolyn J.Molecular Pharmacology

Molecular imaging of cancer and cancer metastasis, inflammation, and other diseases

Apetrei, CristianMolecular Virology & Microbiology

Pathogenesis of natural and nonnatural SIV infection, virus diversity and evolution, and NHP models for cure research

Apodaca, GerardCell Biology & Molecular Physiology

Epithelial cell biology: stretch-regulated exocytic and endocytic traffic and role of uroplakins in kidney development and CAKUT

Arndt, KarenMolecular Genetics & Developmental Biology

Role of chromatin structure, histone modifications, and RNA polymerase II-associated factors in regulating transcription elongation and termination

Badylak, Stephen

Cellular & Molecular Pathology

Regenerative Medicine, macrophage biology, Extracellular matrix, stem cells, liver regeneration and skeletal muscle regeneration

Bakkenist, Christopher J.Molecular Pharmacology

DNA replication and repair signaling by the ATM and ATR protein kinases and the development of kinase inhibitors for cancer treatment

Barak, Yaacov

Cellular & Molecular Pathology

Molecular Genetics & Developmental Biology

Molecular and developmental genetics of the placenta; The life cycle of fat cells – differentiation, death, regeneration
Becker, DorotheaCellular & Molecular Pathology

Identification and analysis of genes that have pertinent functions in cancer progression

Bell, Aaron W.Cellular & Molecular Pathology

Cirrhosis, Liver disease, Alpha-1-antitrypsin deficiency, Transcriptional regulation, animal models

Bernstein, KaraMolecular Genetics & Developmental Biology

Genomic instability (a hallmark of cancer cells).  Analysis of genes that promote accurate repair of DNA damage and genome integrity

Birder, LoriMolecular Pharmacology

Lower urinary tract physiology - focus on epithelium (urothelial) functions; Pathophysiology

Billiar, Timothy R.Cellular & Molecular Pathology

We study aspects of innate immunity in trauma, infection and surgery focusing on: hypoxia mechanisms, danger signals, nitric oxide, liver injury.

Biswas,
Partha S.
Immunology

Cellular and molecular pathogenesis of autoimmune disorders, with an emphasis on understanding the role of IL-17 in end-organ damage

Bomberger, Jennifer

Immunology

Molecular Virology & Microbiology

Mechanisms of Pseudomonas aeruginosa pathogenesis the lung, including the impact of virus co-infection and lipid mediators of inflammation

Borghesi, Lisa

Immunology

HSC biology, pathogen sensing by TLRs, translational studies of chronic inflammation and immune exhaustion

Brodsky, Jeffrey L.

Cell Biology & Molecular Physiology

Molecular Genetics & Developmental Biology

Protein degradation and quality control of proteins linked to human disease, and molecular chaperone-based "decisions" during protein quality control

Butterfield,
Lisa H.
Immunology

The Butterfield Lab investigates human tumor immunology, focusing on analysis of cancer vaccines for melanoma and hepatocellular cancer

Butterworth, Michael B.Cell Biology & Molecular Physiology

Renal microRNAs (miR) linked to regulation of epithelial ion transport.  Hormonal control of miR expression.  Role of miR targets in sodium homeostasis.

Carattino, Marcelo D.Cell Biology & Molecular Physiology

Epithelial transport, ion channels, acid-sensing ion channels, ion channel structure-function, tight junctions, neurons, mechanosensation.

Chan, Stephen Y.Cellular & Molecular Pathology

We study molecular mechanisms of pulmonary hypertension by coupling network-based bioinformatics with unique experimentation in animals and humans.

Chang, Yuan

Cellular & Molecular Pathology

Molecular Virology & Microbiology

Basic mechanisms of healthy cell transformation into cancer cells during viral oncogenesis, and new pathogen discovery

Chu, Charleen

Cellular & Molecular Pathology

Regulation of autophagy and mitophagy, post-translational modifications, kinase pathways, cell survival and neurodegeneration

Clark, Nathan

Molecular Genetics & Developmental Biology

Comparative Genomics & Evolutionary Genetics: Co-evolution and adaptive evolution of proteins, gene networks and cells. Yeast and mammalian models

Coyne, Carolyn

Cell Biology & Molecular Physiology

Molecular Virology & Microbiology

Host-pathogen interactions, virology, innate immunity, cell biology, RNA viruses

D'Cruz, LouiseImmunology

Understanding the molecular mechanisms underlying the immune response of lymphocytes such as Natural Killer T cells as well as innate lymphoid cells

DeFranco, Donald B.Molecular Pharmacology

Impact of glucocorticoids on development of the cerebral cortex and hypothalamus; Estrogen receptor action in prostate cancer and BPH

Delgoffe, Greg M.Immunology

T cell metabolism and responses in the tumor microenvironment; metabolic pathways in effector and regulatory T cells; T cell mitochondrial dynamics

DeLuca, Neal A.

Molecular Genetics & Developmental Biology

Molecular Virology & Microbiology

Interactions of viral and cellular proteins with each other, and with the herpesvirus genome, which mediate productive and latent infections

Dobrowolski, Steven

Cellular & Molecular Pathology

Genomics in intoxicating type inborn errors of metabolism. Methylome repatterning and other epigenome alteration induced by metabolic intoxication

Dong, H. Henry

Cell Biology & Molecular Physiology

Cellular & Molecular Pathology

Pathophysiology of Diabetic Dyslipidemia, Mechanisms of Insulin Resistance, Beta-cell mass and function regulation in obesity and type 2 diabetes.

Duncan, Andrew W.Cellular & Molecular Pathology

The role of chromosome variations in liver biology and disease

Dutta, ParthaImmunology

Understanding the molecular cues of generation of monocytes from their progenitors, their recruitment to inflammatory sites and differentiation into macrophages.

Ferris,
Robert L.
Immunology

Cancer immunology and vaccines, antigen presentation, chemokines; Immunotherapy;  Head and neck neoplasms; Tumor microenvironment; HPV; HNSCC

Flynn,
JoAnne L.

Immunology

Molecular Virology & Microbiology

Tuberculosis; Host-pathogen interactions; Infectious disease; Immunology of tuberculosis; Vaccines

Ford, Marijn

Cell Biology & Molecular Physiology

The role of the dynamin-related proteins in autophagy.

Fox, Ira J.

Cellular & Molecular Pathology

Generation and differentiation of human iPS cells; pathogenesis and treatment of acute liver failure and chronic liver failure in cirrhosis

Gaffen,
Sarah L.

Immunology

Molecular Genetics & Developmental Biology

IL-17 signaling and immunity to fungal pathogens

Galbiati, Ferruccio

Molecular Pharmacology

Role of cellular senescence in cancer and aging

Ghazi, Arjumand

Cell Biology & Molecular Physiology

Molecular Genetics & Developmental Biology

Genetic control of longevity and reproduction role(s) of lipid metabolism and proteostasis pathways in aging stress response and lifespan regulation

Glorioso, Joseph C.

Molecular Genetics & Developmental Biology

Molecular Virology & Microbiology

HSV Vector engineering and gene therapy approaches to the treatment of Chronic Pain; Huntington's disease, and glioblastoma

Goncharova, Elena

Cellular & Molecular Pathology

Molecular and cellular mechanisms of pulmonary arterial hypertension; mTOR and HIPPO signaling networks in VSM phenotype switching in PAH

Hallows, Kenneth

Cell Biology & Molecular Physiology

Epithelial transport regulation and coupling to metabolism and stress by AMPK and other kinases; Acute kidney injury and CKD; CF lung disease; ADPKD

Hammond, Gerry

Cell Biology & Molecular Physiology

Lipid signalling in the control of vascular and airway tension.  Nanoscopic architecture and function of the cell membrane in health and disease.

Hong, Yang 

Cell Biology & Molecular Physiology

Molecular Virology & Microbiology

Control of epithelial polarity and regulation of tumorigenesis by tumor suppressor proteins in Drosophila and mammalian systems
Horn, John P.Molecular Pharmacology

Synaptic signaling in sympathetic neurons that control blood pressure and its modulation by G-protein coupled receptors

Isenberg, Jeffrey S.

Molecular Pharmacology

Cellular & Molecular Pathology

Signal transduction; Matricellular proteins; Pluripotent and self-renewal pathways; Reactive oxygen species; Vascular biology; Blood flow; Tissue engineering; Heart failure; Pulmonary hypertension; Ischemia reperfusion; Aging and senescence

Jiang, YuMolecular Pharmacology

Signaling mechanisms that control mitochondrial metabolism in breast cancer cells

Kalinski, PawelImmunology

Cancer immunotherapy; Biology of dendritic cells; Migration of immune cells; CTL induction; NK cells; Th17 cells; Cancer vaccines; Immune suppression

Kane, Lawrence P.

Immunology

Molecular Pharmacology

Signal transduction pathways that regulate T cell and mast cell activation

Kashlan, Ossama B.

Cell Biology & Molecular Physiology

We aim to understand molecular mechanisms of ion channel regulation.  We use biochemistry, electrophysiology, and structural and computational biology.

Khan,
Saleem A.

Molecular Genetics & Developmental Biology

Molecular Virology & Microbiology

Role of MicroRNAs in human papillomavirus-associated cancers and in aging; Role of DNA helicases in plasmid replication and cellular DNA metabolism

Kim, Jiyun V.Immunology

Dynamic role of microglia in pathogenesis and protection through direct visualization by intravital two photon imaging

Kinchington, Paul (Kip) R.Molecular Virology & Microbiology

Varicella zoster virus: animal models of VZV induced pain: In vitro human neuron modeling of VZV capsid axonal transport, latency and reactivation

Kirkwood,
John M.
Cellular & Molecular Pathology

Translational studies of molecularly targeted agents directed at melanoma and immunomodulators-IFNs and IL's, checkpoint inhibitors, anti CTLA4 & PD1

Kleyman, ThomasCell Biology & Molecular Physiology

Structure/regulation of epithelial Na channels; Regulation of ion channels by mechanical forces; Identifying gene variants that alter blood pressure

Kwiatkowski, Adam V.Cell Biology & Molecular PhysiologyMolecular mechanisms of cell-cell adhesion and cytoskeletal organization in cardiomyocytes; mechanical signaling in contractile systems.
Lamitina, ToddCell Biology & Molecular PhysiologyWe use the nematode C. elegans to investigate the mechanisms underlying age-related neurodegenerative diseases like ALS.
Lee,
Adrian V.
Molecular Pharmacology

Signaling, growth factors, proliferation, RNA, xenograft, precision medicine, personalized medicine, insulin, estrogen receptor, progesterone receptor

Leuba,
Sanford H.
Cell Biology & Molecular Physiology

Single molecular motors on nucleic acid templates; Single nucleosomes; Chromatin fibers

Lokshin,
Anna E.
Cellular & Molecular Pathology

Cancer biomarkers, ovarian cancer, pancreatic cancer

Lucas,
Peter C.
Cellular & Molecular Pathology

NF-kB signaling; relationship between chronic inflammation and the development of breast/liver cancer, metabolic dysfunction, and atherosclerosis

Luo, JianhuaCellular & Molecular Pathology

Identifying new tumor markers by  genome sequencing and copy number analyses using Illumina and Affymetrix platforms

Maricich, StephenMolecular Genetics & Developmental Biology

Mammalian sensory system development and function using advanced genetic techniques to trace cell lineage and manipulate gene expression

Marra,
Kacey G.
Cellular & Molecular Pathology

Adipose-derived stem cells; Peripheral nerve repair; Tissue engineering; Biomaterials and drug delivery; Wound healing

McGeachy, Mandy JImmunology

Mechanisms by which Th17 cells are activated and regulated in the context of inflammation and autoimmunity in mouse models and human disease.

Moore, Patrick S

Cell Biology & Molecular Physiology

Molecular Virology & Microbiology

Human cancer viruses, Kaposi's sarcoma herpesvirus, Merkel cell polyomavirus
Nejak-Bowen, Kari

Cellular & Molecular Pathology

Role of beta-catenin in cholestatic liver disease
Nicotra, Matthew L

Cell Biology & Molecular Physiology

Immunology

The role of autophagy in cell death; The molecular basis of self/non-self recognition in marine invertebrates

Nikiforov, YuriCellular & Molecular Pathology

Thyroid cancer genetics; Mechanisms of chromosomal rearrangements induced by ionizing radiation; Next generation sequencing to discover new mutations

Norris, Karen

Immunology

Molecular Virology & Microbiology

Immunology and infectious diseases, vaccine development, HIV infection, chronic immune activation and aging.

Oesterreich, Steffi

Cellular & Molecular Pathology

Molecular Pharmacology

Hormone response in breast cancer, and mechanism of resistance to therapy

Orwig,
Kyle E.
Molecular Genetics & Developmental Biology

The role of stem cells in spermatogenesis; The effects of cancer treatment on fertility; Develop stem cell technologies to treat infertility

Oury, Tim D.Cellular & Molecular Pathology

The role of the receptor for advanced glycation end products (RAGE) in asthma; The role of RAGE in innate immunity

Pagano,
Patrick J.
Molecular Pharmacology

Discovery of new drugs/factors inhibiting oxidases/stress in cardiovascular disease. Methods: high-throughput, FRET, FRAP, FACS, molecular biology

Palladino, Michael J.Molecular Pharmacology

Mitochondrial and neurodegenerative diseases using molecular genetics.  Mechanisms of pathogenesis and novel therapies

Prochownik, Edward V.Molecular Genetics & Developmental Biology

Role of the Myc oncoprotein in cell growth, metabolism and organ regeneration; Pharmacologic inhibition of Myc oncoproteins

Rajkovic, Aleksandar

Cell Biology & Molecular Physiology

Molecular Genetics & Developmental Biology

Whole genome sequencing in reproductive pathology, genome editing to model human variants, transcriptional control of oocyte differentiation.

Rinaldo, Charles R.Molecular Virology & Microbiology

Antigen presenting cells and T cell immunity in targeting HIV and KSHV infections

Roy, ParthaCell Biology & Molecular Physiology

The two main research interests of our lab are cancer biology (specifically cancer metastasis) and angiogenesis.

Sarkar, Saumendra N.

Immunology

Molecular Virology & Microbiology

Innate immune signaling during virus infection and tumorigenesis.

Scott, Iain

Cellular & Molecular Pathology

Molecular Pharmacology

Our lab focuses on the regulation of mitochondrial metabolism and cellular bioenergetics by protein post-translational modifications.

Scott, Melanie J.

Cellular 7 Molecular Pathology

My lab works on identifying a role for inflammasomes in nonimmune cells, focusing on hepatocyte responses to redox stress, DAMPs and sepsis/infection.

Role of inflammasome and caspase-11 in Ehrlichia infection - tick-borne obligate intracellular bacteria that causes sepsis and liver failure/damage

Shair, KathyMolecular Virology & Microbiology

Oncogenic mechanisms and regulation of Epstein-Barr virus (EBV) infection in human cancers.

Shanks, Robert M.Q.Molecular Virology & Microbiology

Microbial pathogenesis, host-pathogen interactions, bacteria-bacteria interactions, microbial genetics

Shlomchik, MarkImmunology

We elucidate the functions of memory B cells using unique cellular systems, molecular genetics, genomic and epigenetic methods.  We also study SLE.

Sims-Lucas, Sunder

Cell Biology & Molecular Physiology

Molecular Genetics & Developmental Biology

Kidney development, blood flow and vascular patterning of the kidney. Acute kidney injury, a common pathological complication leading ESRD.

Sluis-Cremer, Nicolas

Molecular Virology & Microbiology

HIV latency in resting CD4+ T cells subsets; HIV drug resistance in resource limited settings; Structure-function studies of HIV reverse transcriptase

Smithgall, Tom

Molecular Genetics & Developmental Biology

Molecular Pharmacology

Molecular Virology & Microbiology

Protein-tyrosine kinase structure, function, and drug targeting in cancer and HIV/AIDS

Sorkin, AlexanderCell Biology & Molecular Physiology

Mechanism and function of EGF receptor endocytosis in cancer cells; Mechanism and function of endocytosis of the dopamine transporter in the brain

St. Hilaire, CynthiaCellular & Molecular Pathology

We use in vitro and in vivo disease models to study molecular mechanisms underlying vascular disease pathologies.

Straub, AdamMolecular Pharmacology

Molecular and cellular mechanisms of pulmonary vascular physiology and disease

Subramanya, Arohan R.Cell Biology & Molecular Physiology

Molecular processes that define how the kidney coordinates salt reabsorption, potassium secretion, and blood pressure

Tang, PeiMolecular Pharmacology

Drug action on the neurotransmitter-gated receptor channels; Structures and functions of ion channels; Channel related diseases

Thibodeau, Patrick H.Cell Biology & Molecular Physiology

Molecular basis of disease, including cystic fibrosis and metabolic diseases associated with ABC-transporters, and host pathogen interactions in CF

Traub,
Linton M.

Cell Biology & Molecular Physiology

Cellular & Molecular Pathology

We study molecules and mechanisms of receptor-mediated endocytosis using a variety of approaches, ranging from structural biology to animal models

Tsang, MichaelMolecular Genetics & Developmental Biology

Zebrafish, heart development, and regeneration

Tuan, Rocky S.

Cellular & Molecular Pathology

Molecular Genetic & Developmental Biology

Stem cell & regenerative medicine; skeletal development - differentiation, patterning, ECM, & growth factors; 3D printing; tissue chip; microgravity

Turnquist, Heth R.Immunology

Pro-inflammatory vs. regulatory capacity of myeloid cells and cytokines in order to develop new therapies improving transplant outcomes

Tzounopoulos, ThanosMolecular Pharmacology

Circuit, synaptic and intrinsic neuronal mechanisms that are involved during normal and pathological auditory processing

Vignali, Dario AImmunology

Cancer Immunology and Autoimmunity - negative regulatory mechanisms (inhibitory receptors and Tregs) in murine models and human patient samples.

Vilardaga,
Jean-Pierre
Molecular Pharmacology

G protein-coupled receptors; Signaling and trafficking;  Molecular pharmacology of GPCR; GPCR structure and function; parathyroid hormone

Vo, NamCellular & Molecular Pathology

Molecular mechanisms of low back pain: impacts of genomic instability on NF-kB signaling and cellular senescence in pathological aging of the spine.

Wang, XiaosongCellular & Molecular Pathology

Cancer genomics and molecular target discovery, translational cancer biology, integrative bioinformatics to identify cancer targets from big genomic data.

Wei, XiangyunMolecular Genetics & Developmental Biology

The functions of polarity proteins in regulating retinal development; Retinal gene expression regulations in three-dimensional nuclear space

Weisz, Ora A.

Cell Biology & Molecular Physiology

Molecular Virology & Microbiology

We study how biosynthetic and endocytic traffic in the kidney are regulated by physiological cues.

Wells, AlanCellular & Molecular Pathology

How cells interact with and respond to their microenvironment during cancer dissemination and wound healing; Bio-engineered and stem cell therapies

Wenzel,
Sally E.

Cellular & Molecular Pathology

Severe asthma, clinical phenotypes & pathobiology of asthma, role of epithelial cells in controlling airway inflammatory responses

Williams, John V.

Immunology

Molecular Virology & Microbiology

Human metapneumovirus pathogenesis and immunity; vaccines; lung T cell impairment; antibodies

Wipf, PeterMolecular Pharmacology

Medicinal chemistry, chemical biology, and natural products total synthesis

Wu, CaryCellular & Molecular Pathology

Mechanism of integrin-mediated cell-extracellular matrix adhesion, signaling, and its role in cancer and other diseases

Xiao, GutianMolecular Genetics & Developmental Biology

To elucidate the signaling transduction pathways involved in cancer pathogenesis and therapy resistance for cancer prevention and treatment

Xie, WenMolecular Pharmacology

Nuclear receptor-mediated transcriptional regulation of genes that control chemical and functional homeostasis of endogenous and exogenous chemicals

Yang, LeiMolecular Genetics & Developmental Biology

Studying human heart development and heart disease using human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells

Yu, JianCellular & Molecular Pathology

The roles and regulation of cell death in normal and cancerous tissues, and mechanism-based development of cell death-targeted therapeutics

Zarnegar, RezaCellular & Molecular Pathology

My laboratory is interested in deciphering the molecular mechanisms by which HGF/MET regulate cell growth and metabolism

We are also studying HGF gene mutation in breast and colon cancer and how to target HGF/MET axis in cancer

Zarour, Hassane M.Immunology

Cancer immunology, cancer immunotherapy, cancer vaccines, T cell immunology, mechanisms of tumor-induced immunosuppression, melanoma

Zhang, LinMolecular Pharmacology

Molecular mechanisms of differential response to anticancer drugs